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. 2023 Sep 14;24(18):14092. doi: 10.3390/ijms241814092

Figure 4.

Figure 4

The expression levels of the genes regulating cholesterol synthesis are altered in the retinas of 4 M and 12 M 5xFAD and 12 M WT mice while the expression levels of the genes regulating cholesterol transport remain unchanged in all the groups analyzed. The expression levels of Lxrβ mRNA (A), Hmgcr mRNA (B), Abca (C), and ApoE (D) were analyzed in the retinas from 4 M and 12 M 5xFAD and WT mice using real-time polymerase chain reaction (qRT-PCR). Data are presented as mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.