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. 2023 Sep 14;24(18):14092. doi: 10.3390/ijms241814092

Figure 5.

Figure 5

The expression levels of Aqp4 mRNA and protein were increased in the retinas of 4 M and 12 M 5xFAD and 12 M WT mice. (A) The changes in the expression levels of Aqp4 mRNA. (B) The representative immunostaining of Aqp4 in the retinas of 4 M and 12 M, WT and 5xFAD mice. Aqp4—red, DAPI—blue. (C) The changes in the protein expression levels of Aqp4 measured with ImageJ analysis. Scale bar—50 μm. The data represent mean ± SEM value. * p < 0.05, *** p < 0.001, **** p < 0.0001. ns—not significant, ONL—outer nuclear layer, INL—inner nuclear layer.