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. 2023 Sep 5;12(18):5783. doi: 10.3390/jcm12185783

Table 2.

Mechanical ventilation use during the first day of mechanical ventilation.

COPD
Patients
N = 88		 Non-COPD
Patients
N = 1002		 p-Value
Mode of mechanical ventilation, n (%) 0.12
Volume-controlled 18 (21) 143 (14)
Pressure-controlled 41 (47) 561 (56)
Pressure support 3 (3) 50 (5)
SIMV 9 (10) 72 (7)
APRV 5 (6) 27 (3)
INTELLiVENT–ASV 5 (6) 36 (4)
Other 6 (7) 109 (11)
Ventilation Parameters
Expiratory VT, mL, median [IQR] 440 [387–498] 451 [408–502] 0.13
VT per PBW, mL/kg, median [IQR] 6.2 [5.9–7.0] 6.4 [5.9–7.0] 0.67
PEEP, cmH2O, median [IQR] 13 [12–15] 13 [11–15] 0.24
Total Respiratory rate, median [IQR] 22 [20–24] 22 [19–24] 0.84
FiO2, median [IQR] 0.6 [0.5–0.7] 0.6 [0.5–0.7] 0.01
Ppeak, cmH2O, median [IQR] 27 [24–29] 27 [24–30] 0.78
Driving pressure, cmH2O, median [IQR] 14 [12–16] 14 [12–16] 0.87
Compliance, cmH2O/L, median [IQR] 32 [26.8–39] 33 [27–40] 0.70
Mechanical power, J/min, median [IQR] 18 [15–20] 19 [16–22] 0.07
Minute ventilation, L/min, median [IQR] 9 [8–10] 10 [8–11] 0.07
pH, median [IQR] 7.35 [7.29–7.39] 7.37 [7.31–7.41] 0.02
PaO2, kPa, median [IQR] 10 [9–12] 11 [9–13] 0.08
PaO2/FiO2, mmHg, median [IQR] 114 [89–149] 128 [99–168] 0.01
PaCO2, kPa, median [IQR] 6.1 [5.5–6.5] 5.9 [5.2–6.7] 0.25
End-tidal CO2, kPa, median [IQR] 4.6 [4.1–5.3] 4.9 [4.4–5.6] 0.01
Dead space fraction, median [IQR] 0.24 [0.14–0.33] 0.16 [0.06–0.26] <0.001

Abbreviations: APRV, airway pressure release ventilation; ASV, adaptive support ventilation; COPD, chronic obstructive pulmonary disease; FiO2, fraction of inspired oxygen; IQR; interquartile range; J/min, joules per minute; kg, kilogram; kPa, kiloPascal; mL, milliliter; PaCO2, arterial pressure of carbon dioxide; PaO2, arterial pressure of oxygen; PBW, predicted body weight; PEEP, positive end-expiratory pressure; Ppeak, peak airway pressure; SIMV, synchronized intermittent mandatory ventilation; VT, tidal volume.