Figure 3.

Schematic diagram of the pathogenesis of atherosclerosis. Downward arrows indicate decrease in level. Abbreviations: ABCA1 ATP binding cassette A1, ACAT acyl CoA:cholesterol acyltransferase, CCL C-C motif chemokine ligand, CXCL CXC chemokine ligand, eNOS endothelial nitric oxide synthase, ICAM-1 intercellular adhesion molecule-1, IL interleukin, NF-κB nuclear factor kappa-B, NLRP3 nod-like receptor family pyrin domain containing 3, oxLDL oxidised low-density lipoprotein, PDGF platelet-derived growth factor, PECAM-1 platelet endothelial cell adhesion molecule-1, ROS reactive oxygen species, TNF-α tumour necrosis factor-α, VCAM-1 vascular cell adhesion molecule.