Table 5.
Spontaneous platelet activation in citrated whole blood, assessed by expression of P-selectin (CD62P), after contact with the tested biomaterials. Evaluation results are presented as fluorescence intensity (a.u.) and represent the mean values and standard deviations (MEAN ± SD) of four independent experiments with three replicates of each sample (n = 12). For negative and positive controls n = 48. Explanations of other symbols are in the text. Statistical significance levels are marked with asterisks as follows: * p < 0.05, *** p < 0.001, ns—not significant.
| A Grinding |
B Polishing |
C Rosette Like |
D Crater Like |
Significance | |
|---|---|---|---|---|---|
| AISI 316L {1} |
308 ± 161 | 348 ± 190 | 470 ± 236 | 258 ± 87 | * C–D |
| CoCrMo {2} |
322 ± 137 | 250 ± 87 | 443 ± 271 | 236 ± 80 | * C–D, *** A–D, B–D |
| Ti6Al4V {3} |
345 ± 210 | 246 ± 61 | 410 ± 189 | 286 ± 121 | ns |
| Ti6Al7Nb {4} |
327 ± 171 | 246 ± 62 | 421 ± 199 | 281 ± 76 | * B–C |
| negative control {5} | 350 ± 173 | *** {5}–{6} | |||
| positive control {6} | 534 ± 429 | ||||
| significance | ns | ns | ns | ns | |