ABTS |
2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) |
AKT |
protein kinase B |
AUC |
area under the curve |
BACE1 |
beta-site amyloid precursor protein cleaving enzyme |
CAT |
catalase |
α-CD |
α-cyclodextrin |
β-CD |
β-cyclodextrin |
γ-CD |
γ-cyclodextrin |
CDs |
cyclodextrins |
COX-2 |
cyclooxygenase 2 |
CryoTEM |
cryogenic transmission electron microscopy |
DIMEB |
heptakis-(2,6-di-O-methyl)-β-cyclodextrin |
DMPC |
dimyristoyl phosphatidylcholine |
DODA-GLY-PEG2000
|
2-dioctadecylcarbamoyl-methoxyacetylamino) acetic acid (ω-methoxy)-polyethylene glycol 2000 ester |
DOPC |
1,2-dioleoyl-sn-glycero-3-phosphocholine |
DSC |
Differential Scanning Calorimetry |
EMA |
European Medicines Agency |
ERK |
extracellular signal-regulated kinases |
FAK |
focal adhesion kinase |
FDA |
Food and Drug Administration |
FGFR1 |
fibroblast growth factor receptor |
FIS-β-CD |
fisetin β-cyclodextrin complex |
FIS-HP-β-CD |
fisetin 2-Hydroxypropyl-β-cyclodextrin complex |
FRAP |
ferric reducing antioxidant power assay |
GSH |
reduced glutathione |
GSK-3 β |
glycogen synthase kinase 3 beta |
GPx |
glutathione peroxidase |
GRAS |
generally recognized as safe |
HaCaT |
Cultured Human Keratinocyte |
HP-β-CD |
2-Hydroxypropyl-β-cyclodextrin |
HPC |
hydroxypropyl cellulose |
HPMC |
hydroxypropyl methylcellulose |
HSA-NPs |
human serum albumin nanoparticles |
IL-1α |
interleukin-1α |
IL-1β |
interleukin-1β |
IL-6 |
interleukin 6 |
IL-8 |
interleukin 8 |
iNOS |
inducible nitric oxide synthase |
iRhom2 |
the inactive rhomboid protein 2 |
LDL |
low-density lipoprotein |
LL/2 |
Lewis lung carcinoma cell line |
LLC |
Lewis lung carcinoma |
MAPK |
mitogen-activated protein kinases |
MPEG-PCL |
methoxy poly(ethylene glycol)-poly(ε-caprolactone) |
mTOR |
serine-threonine protein kinase |
mTORC2
|
mammalian target of rapamycin complex 2 |
NLRP3 |
the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing 3 |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NO |
nitric oxide |
NPs |
nanoparticles |
Nrf2 |
nuclear factor erythroid 2-related factor 2 |
ORAC |
oxygen radical absorbance capacity |
PCL |
poly-(ε-caprolactone) |
PCOS |
polycystic ovary syndrome |
PGE2
|
prostaglandin E2 |
PI3K |
phosphoinositide-3-kinase |
PLA |
poly(lactic acid) |
PLGA |
poly(lactic-co-glycolic acid |
PLGA-PEG-COOH |
poly(D,L-lactic-co-glycolic acid)-block-poly(ethylene glycol) carboxylic acid |
PPAR-γ |
the peroxisome proliferators-activated receptors gamma |
PTEN |
phosphatase and tensin homolog deleted on chromosome 10 |
PVA |
polyvinyl alcohol |
PVP |
poly(vinylpyrrolidone) |
QABCD |
quaternary ammonium β-cyclodextrin |
RAMEB |
randomly methylated β-cyclodextrin |
ROS |
reactive oxygen species |
SBE-β-CD |
sulfobutylether β-cyclodextrin |
SHPβ-CD |
succinyl-2-hydroxypropyl β-cyclodextrin |
SLN |
solid lipid nanoparticles |
SLS |
sodium lauryl sulfate |
SNEDDS |
self-nonoemulsifying drug delivery system |
SOD |
superoxide dismutase |
TLR4 |
toll-like receptor 4 |
TNF-α |
tumor necrosis factor-alpha |
TRAIL |
tumor necrosis factor-related apoptosis-inducing ligand |
VEGF |
vascular endothelial growth factor |