Table 2.

A summary of proposed outcome measures for different stages of disease.

Stage	Defining Characteristics	Potentially Appropriate Outcome Measures
Early stage	Rod degeneration in the mid-peripheral region with some secondary cone involvement and reduced para-central retinal sensitivity.	- Full field perimetry (static) - Mesopic/scotopic microperimetry - Patient-reported outcomes - OCT - FAF - Infrared AF
Moderate stage	Radial advancement of rod and secondary cone degeneration with a scotomatous mid-peripheral region and reduced retinal sensitivity encroaching the macula.	- Full field perimetry (static or kinetic) - Mesopic microperimetry - Patient-reported outcomes - OCT - FAF - BCVA/LLVA
Late stage	Defined by the encroachment of scotomas and/or reduced sensitivity well within the vascular arcades and encroaching the central region (Figure 1 and Figure 2).	- Full field perimetry (static or kinetic) - Mesopic microperimetry - Patient-reported outcomes - OCT (Figure 3) - FAF - FST - BCVA/LLVA