Table 1.
Factors associated with in-hospital mortality among blastomycosis-associated hospitalizations, 2010 to 2020.
| Total | Died | Survived | ||
|---|---|---|---|---|
| Characteristic | n = 11,776 | n = 928 | n = 10,848 | p-Value |
| Mean age, years (standard error [SE]) | 53.6 (0.48) | 61.8 (1.03) | 53.0 (0.51) | <0.001 |
| Age group, years | <0.001 | |||
| <18 | 344 (2.9%) | not shown 1 | not shown 1 | |
| 18 to 44 | 3212 (27.3%) | 94 (10.1%) | 3118 (28.7%) | |
| 45 to 64 | 4552 (38.7%) | 413 (44.5%) | 4139 (38.2%) | |
| ≥65 | 3668 (31.1%) | 416 (44.8%) | 3252 (30.0%) | |
| Sex | 0.567 | |||
| Male | 7218 (61.3%) | 598 (64.4%) | 7218 (66.5%) | |
| Female | 3959 (33.6%) | 330 (35.6%) | 3629 (33.5%) | |
| Hospital region | 0.127 | |||
| Northeast | 643 (5.5%) | 33 (3.6%) | 610 (5.6%) | |
| Midwest | 6921 (58.8%) | 519 (55.9%) | 6401 (59.0%) | |
| South | 3702 (31.4%) | 350 (37.7%) | 3352 (30.9%) | |
| West | 510 (4.3%) | 25 (2.7%) | 485 (4.5%) | |
| Race/ethnicity (n = 10,994) | 0.079 | |||
| White | 7315 (66.5%) | 627 (75.2%) | 6687 (65.8%) | |
| Black | 1859 (16.9%) | 94 (11.3%) | 1765 (17.4%) | |
| Hispanic | 976 (8.9%) | 53 (6.4%) | 923 (9.1%) | |
| Other race/ethnicity | 845 (7.7%) | 60 (7.2%) | 785 (7.7%) | |
| Payer (n = 11,730) | <0.001 | |||
| Medicare | 4941 (42.1%) | 524 (56.8%) | 4417 (40.9%) | |
| Medicaid | 2009 (17.1%) | 99 (10.7%) | 1910 (17.7%) | |
| Private insurance | 4363 (37.2%) | 266 (28.8%) | 4097 (37.9%) | |
| Other payer | 418 (3.6%) | 34 (3.7%) | 384 (3.6%) | |
| Income quartile for patient’s ZIP code (n = 11,562) | 0.575 | |||
| 0 to 25th percentile | 4102 (35.5%) | 337 (37.3%) | 3765 (35.3%) | |
| 26th to 50th percentile | 3430 (29.7%) | 292 (32.3%) | 3138 (29.4%) | |
| 51st to 75th percentile | 2543 (22.0%) | 182 (20.2%) | 2361 (22.2%) | |
| 76th to 100th percentile | 1488 (12.9%) | 93 (10.3%) | 1395 (13.1%) | |
| Admission season | 0.182 | |||
| Winter | 2937 (25.1%) | 261 (28.3%) | 2676 (24.8%) | |
| Spring | 3343 (28.5%) | 223 (24.2%) | 3120 (28.9%) | |
| Summer | 2860 (24.4%) | 195 (21.1%) | 2665 (24.7%) | |
| Fall | 2577 (22.0%) | 244 (26.4%) | 2333 (21.6%) | |
| Concurrent conditions | ||||
| Autoimmune inflammatory disease | 703 (6.0%) | 54 (5.8%) | 648 (6.0%) | 0.954 |
| Chronic obstructive pulmonary disease (COPD) | 2454 (20.8%) | 256 (27.6%) | 2198 (20.3%) | 0.020 |
| Diabetes | 3590 (30.5%) | 298 (32.1%) | 3652 (33.7%) | 0.836 |
| Hematologic malignancy | 729 (6.2%) | 100 (10.8%) | 629 (5.8%) | 0.008 |
| HIV infection | 387 (3.3%) | 39 (4.2%) | 348 (3.2%) | 0.462 |
| Solid malignancy | 989 (8.4%) | 143 (15.4%) | 846 (7.8%) | <0.001 |
| Solid organ or stem cell transplant | 549 (4.7%) | 25 (2.7%) | 524 (4.8%) | 0.178 |
| Mean length of hospitalization, days (SE) | 9.9 (0.25) | 14.0 (0.93) | 9.6 (0.25) | <0.001 |
| Clinical form of blastomycosis 2 | n = 5595 | n = 480 | n = 5115 | |
| Pulmonary | 2970 (53.1%) | 300 (62.5%) | 2670 (52.2%) | 0.055 |
| Cutaneous | 295 (5.3%) | 20 (4.2%) | 275 (5.4%) | 0.613 |
| Disseminated | 870 (15.5%) | 80 (16.7%) | 790 (15.4%) | 0.754 |
| Other or unspecified form | 1730 (30.9%) | 110 (22.9%) | 1620 (31.7%) | 0.076 |
1 Because of HCUP reporting restrictions, cells with ≤10 hospitalizations or cells that would enable calculation of a cell ≤10 are not displayed. 2 Among hospitalizations with ICD-10-CM data.