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. 2023 Aug 28;13(9):1819. doi: 10.3390/life13091819

Table 1.

Pros and cons of current cerebral protection devices.

Device Pros Cons
ProtEmbo CPS [38] Small size sheath (6 Fr);
Left radial/brachial access;
Mesh with the smallest pore size available;
100% successful device positioning.		 Partial coverage of the supra-aortic trunk;
New cerebral lesions were detected, but smaller;
Available evidence only for TAVR.
Embrella [30] Small size sheath (6 Fr);
Right radial/brachial access;
100% successful device positioning.		 Partial coverage of the supra-aortic trunk;
New cerebral lesions were detected, but smaller;
Available evidence only for TAVR.
TriGuard 3 [36,42] Intermedium size sheath (9 Fr);
Implantable through both the left and right femoral arteries;
Full coverage of the supra-aortic trunk;
Can be left in the aortic arch for days;
100% successful device positioning;
Large amount of evidence;
Available evidence for TAVR, LAAC, and VT ablation.		 Femoral access;
Procedural concerns if transcatheter procedure performed through the retro-aortic path;
New cerebral lesions were detected, but smaller.
Sentinel [36,43] Small size sheath (6 Fr);
Right radial/brachial access;
94.4% successful device positioning;
Largest amount of evidence;
Available evidence for TAVR, LAAC, and VT ablation.		 Partial coverage of the supra-aortic trunk;
New cerebral lesions were detected but smaller.
Emblok [41] Implantable through both the left and right femoral arteries;
100% successful device positioning.		 Intermedium size sheath (11 Fr);
Femoral access;
Procedural concerns if transcatheter procedure performed through the retro-aortic path;
New cerebral lesions were detected, but smaller;
Available evidence only for TAVR.
Wirion [31] Small size sheath (6 Fr);
Right radial/brachial access;
Very low amount of evidence.		 Nonsufficient coverage of the supra-aortic trunk;
Available evidence only for TAVR;
Emboliner Coverage of the supra-aortic trunk and descending aorta;
Implantable through both the left and right femoral arteries. 		Data on the first-in-man study is not yet available.
Capitis Coverage of the supra-aortic trunk and descending aorta;
Implantable through both the left and right femoral arteries. 		Data on the first-in-man study is not yet available.