Skip to main content
. 1998 Nov;36(11):3359–3361. doi: 10.1128/jcm.36.11.3359-3361.1998

TABLE 1.

Evaluation of IgM ELISA based on recombinant EBV 18-kDa matrix protein antigen for the diagnosis of primary EBV infection and comparison with reference assays and heterophile antibody tests

Results of reference tests
No. of sera Consensus interpretation of reference test results No. (%) of sera positive by:
EBV VCA IgM IF EBV VCA IgG IF EBNA antibody EBV VCA IgM ELISA Heterophile antibody test
Concordant results
 Positive Positive Negative 23 Recent primary EBV infection 22 (96) 9 (39)
 Negative Positive Positive 56 Past EBV infection 3 (5) 1 (2)
 Negative Negative Negative 28 No evidence of recent or past EBV infection 0 (0) 1 (4)
Discordant results
 Negative Positive Negative 9 Discordant results in reference testsa 1 (11) 1 (11)
 Positive Positive Positive 1 Discordant results in reference testsb 1 0
a

VCA IgG-EBNA profile suggested recent infection, but no VCA IgM was detected by IF test. 

b

VCA IgM IF test indicated recent infection, but positive EBNA antibody suggested past infection.