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. 2023 Sep 20;13(9):1414. doi: 10.3390/jpm13091414

Table 3.

Pairwise comparisons of the association between the change in proteinuria status and the risk of incident hypertension.

Model 1 Model 2 Model 3
HR (95% CI) p-Value HR (95% CI) p-Value HR (95% CI) p-Value
Proteinuria-resolved vs. Proteinuria-free (reference) 1.19 (1.15, 1.23) <0.001 1.17 (1.13, 1.21) <0.001 1.17 (1.13, 1.21) <0.001
Proteinuria-developed vs. Proteinuria-free (reference) 1.31 (1.27, 1.36) <0.001 1.31 (1.27, 1.35) <0.001 1.31 (1.26, 1.35) <0.001
Proteinuria-resolved vs. Chronic proteinuria (reference) 0.46 (0.43, 0.50) <0.001 0.58 (0.53, 0.63) <0.001 0.58 (0.53, 0.63) <0.001
Proteinuria-developed vs. Chronic proteinuria (reference) 0.52 (0.48, 0.56) <0.001 0.65 (0.59, 0.70) <0.001 0.65 (0.60, 0.71) <0.001

Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex, body mass index, household income, smoking, alcohol consumption, physical activity, history of diabetes mellitus, dyslipidemia, atrial fibrillation, cancer, and renal disease. Model 3 was adjusted for age, sex, body mass index, household income, smoking, alcohol consumption, physical activity, history of diabetes mellitus, dyslipidemia, atrial fibrillation, cancer, renal disease, and Charlson Comorbidity Index. HR, hazard ratio; CI, confidence interval.