Table 4.
Subgroup analysis of multivariable Cox analysis for incident hypertension according to changes in proteinuria status.
| With Renal Diseases | ||||
| Proteinuria Status | Total (n) | Hypertension (n) | Incidence Rate (per 1000 Person Years) | Adjusted HR (95% CI) * |
| Proteinuria-free | 2532 | 1562 | 70.94 | 1 (ref) |
| Proteinuria-resolved | 76 | 56 | 98.21 | 1.46 (1.12, 1.91) |
| Proteinuria-developed | 48 | 33 | 88.31 | 1.43 (1.01, 2.02) |
| Chronic proteinuria | 29 | 25 | 185.34 | 2.62 (1.76, 3.91) |
| p for trend | <0.001 | |||
| Without Renal Diseases | ||||
| Proteinuria Status | Total (n) | Hypertension (n) | Incidence Rate (per 1000 Person Years) | Adjusted HR (95% CI) * |
| Proteinuria-free | 916,512 | 337,698 | 31.42 | 1 (ref) |
| Proteinuria-resolved | 7412 | 3075 | 37.02 | 1.16 (1.12, 1.21) |
| Proteinuria-developed | 8157 | 3605 | 41.05 | 1.30 (1.26, 1.35) |
| Chronic proteinuria | 957 | 632 | 79.61 | 2.08 (1.92, 2.25) |
| p for trend | <0.001 | |||
* Adjusted for age, sex, body mass index, household income, smoking, alcohol consumption, physical activity, history of diabetes mellitus, dyslipidemia, atrial fibrillation, cancer, renal disease, and Charlson Comorbidity Index. HR, hazard ratio; CI, confidence interval.