Figure 2.

Schematic of the metabolic pathways and key enzymes for the production of sugar alcohols in yeasts. ZWF: glucose-6-phosphate 1-dehydrogenase; GNL: 6-phosphogluconolactonase; GND: 6-phosphogluconate dehydrogenase; TKL: transketolase; TAL: transaldolase; PGI: phosphoglucose isomerase; E4PK: erythrose-4-phosphate kinase; ER: erythrose reductase; EYD: erythrulose dehydrogenase; SsXDH: xylitol dehydrogenase gene from Scheffersomyces stipitis; EYK: erythrulose kinase; E4PP: erythrose 4-phosphate phosphatase; GUT1: glycerol kinase; GUT2: glycerol 3-phosphate dehydrogenase; HXK: hexokinase; MtlD: mannitol-1-phosphate dehydrogenase; M1pp: mannitol-1-phosphate phosphatase; FFZ1: fructose transporter; MTDH1: mannitol dehydrogenase; E4P: erythrose-4-phosphate; Gly-3-P: glyceraldehyde-3-P; DHAP: dihydroxyacetone phosphate.