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. 2023 Sep 27;14:6040. doi: 10.1038/s41467-023-41721-9

Fig. 2. AFM screen between 1879 SSPs and 6 hydrolases identifies 376 candidate complexes.

Fig. 2

a 1879 proteins from seven tomato pathogens that are likely secreted and small (<35 kDa) were screened for complexes with six secreted defense-related hydrolases of tomato using AlphaFold-Multimer (AFM). The best of the five generated AFM models for each of the 11,274 protein pairs were selected if the ipTM + pTM score was 0.75 or higher, resulting in 376 putative complexes. b best ipTM + pTM scores for all the 11,274 complexes involving 1879 small secreted proteins (SSPs) of the seven tomato pathogens listed on the bottom. Symbols for complexes with the six different hydrolases (explained in (a)) highlight the 376 candidate complexes with ipTM + pTM ≥ 0.75. The best and all ipTM + pTM values for each protein pair used for this figure are provided in Supplementary Data 7 and Supplementary Data 8, respectively.