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. 2023 Aug 2;19(11):1030–1040. doi: 10.1007/s12519-023-00743-5

Table 1.

Inclusion and exclusion criteria using the PICO format

Variables Common clinical manifestations Rehabilitation
Population characteristics RSV-infected children aged five years and younger
Intervention or exposure RSV infection in the first five years of life
Comparator (s) a RSV-negative children
Outcomes Common clinical manifestations Wheezing illnessb
Study design Cohort study, cross-sectional study, case–control study, case-cohort study, and nested case–control study Case–control study, case-cohort study, and cohort study
Year published January 1, 2010 to June 2, 2022
Sample size More than 100
Exclusion (1) Adults, the elderly, or children over the age of five; (2) unhealthy children, children with congenital heart disease or immunodeficiency disease, etc.; (3) reported composition ratio; (4) comparison of two RSV detection methods; (5) studies on languages other than Chinese and English; (6) animal research, repeated publications, letters, comments, case reports, case series, editorials, reviews, pure model studies, or model studies for trend estimation; (7) full text that was not available; and (8) only articles with the most comprehensive data were included in the repeated articles

PICO population, intervention or exposure, comparators, and outcomes RSV respiratory syncytial virus

aTo calculate a single proportion of each clinical manifestation, and no comparator variables for this section

bBecause studies did not use consistent definitions for asthma and other wheezing illnesses, all variations of wheezing illness were combined into a single outcome