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. 2023 Sep 27;14:6021. doi: 10.1038/s41467-023-41046-7

Fig. 4. Monolayer MoS2 memtransistor-based “hunger neuron” and “appetite neuron”.

Fig. 4

a Optical image and b circuit schematic of a representative comparator circuit composed of 8 MoS2 memtransistors (MT1MT8) used as the “hunger neuron” and the “appetite neuron”. The comparator circuit is a 4-stage cascaded inverter as each memtransistor pair, MT1MT2, MT3MT4, MT5MT6, and MT7MT8 serve as an inverter. c VN4 measured at node, N4. d VN5 measured at node, N5. e VN6 measured at node, N6, and f VN7 measured at node, N7, as a function of the input voltage, VN2, applied to node N2. Peak gain for each inverter stage is mentioned in the inset. Highest gain of ~90 is observed for the output stage, which allows for the abrupt state transition for VN7 from 0 to VDD, i.e., logic “0” to logic “1”. The input voltage, VN2, at which this sharp state transition occurs is referred to as the comparator threshold (VTHC). For the “hunger neuron” and the “appetite neuron”, VTHC is represented by VHN and VAN, respectively, and VN7 is represented by logic state variables H and A, respectively. Temporal evolution of VH, i.e., logic state of H in response to g sweet and h bitter taste stimulants. Temporal evolution of VA, i.e., logic state of A in response to i sweet and j bitter taste stimulants. k Transfer curve for the “appetite neuron” for different VAN obtained through non-volatile programming of MoS2 memtransistor, MT2. Corresponding temporal evolution of VA or A in response to l sweet and m bitter taste stimulants.