. Author manuscript; available in PMC: 2023 Sep 28.

Published in final edited form as: Allergy. 2023 Jan 24;78(6):1595–1604. doi: 10.1111/all.15644

TABLE 3.

Microbiome predominant in FPIES versus controls at different age bins

Age bin	Group	MaAsLin2	ANCOM	LEfSe
0–3 months	FPIES	Bacteroides fragilis Ruminococcus bromii Parabacteroides distasonis Clostridium baratii Bacteroides spp. Holdemania spp. Lachnobacterium spp. Sutterella spp. Phascolarctobacterium spp. Anaerotruncus spp.	None	Clostridium perfringens Bacteroides caccae Ruminococcus bromii Gemmiger formicilis Bacteroides ovatus Holdemania spp. Lachnobacterium spp.
0–3 months	Controls	Bifidobacterium spp.	Bifidobacterium adolescentis	Bifidobacterium adolescentis Veillonella parvula Ruminococcus gnavus Clostridium neonatale Clostridium butyricum Rothia mucilaginosa Roseburia faecis Faecalibacterium prausnitzii Bifidobacterium spp. Parabacteroides spp. Clostridium spp. Streptococcus spp. Anaerococcus spp. Finegoldia spp. Roseburia spp. Corynebacterium spp.
4–6 months	FPIES	Bacteroides fragilis ^*		Acinetobacter lwoffii
4–6 months	Controls	None	Bifidobacterium adolescentis	Bifidobacterium adolescentis Ruminococcus gnavus Veillonella dispar Faecalibacterium prausnitzii Bifidobacterium spp.

Note: The q-value of all bacteria <.05 except the one marked with asterisk.

p = 2.92 × 10⁻⁴, q = .06.