Table 3.
Age-standardised trends for cause-specific anaphylaxis event rates
| Average annual % change (95% CI)a |
||||||
|---|---|---|---|---|---|---|
| 2010–2019 |
2010–2014 |
2015–2019 |
||||
| Males | Females | Males | Females | Males | Females | |
| Food | ||||||
| all ages | 1.8 (0.3–3.4) | 4.7 (3.2–6.3) | −1.5 (−5.9 to 3.0) | 2.7 (−1.9 to 7.5) | 5.0 (0.7–9.5) | 10.2 (5.9–14.8) |
| <1y | −2.0 (−7.3 to 3.7) | 4.4 (−2.5 to 11.7) | −13.9 (−26.8 to 1.1) | −0.9 (−19.1 to 21.3) | 4.1 (−11.2 to 22.2) | 11.5 (−7.1 to 33.8) |
| 1-4y | −3.8 (−6.9 to −0.6) | 1.4 (−3.2 to 6.2) | −3.4 (−11.8 to 5.8) | −3.2 (−15.4 to 10.8) | −3.3 (−12.2 to 6.6) | 8.1 (−4.9 to 22.9) |
| 5-14y | 3.8 (0.8–7.0) | 7.4 (3.5–11.5) | 7.3 (−2.2 to 17.7) | 1.9 (−9.7 to 14.8) | −0.5 (−8.1 to 7.8) | 3.5 (−5.7 to 13.5) |
| 15-24y | 3.9 (0.2–7.8) | 4.7 (1.5–8.1) | −2.2 (−12.3 to 9.0) | 0.4 (−8.6 to 10.3) | 10.7 (0.2–22.4) | 12.0 (2.8–22.1) |
| 25-34y | 4.0 (−0.8 to 9.1) | 0.0 (−3.8 to 3.9) | −8.2 (−20.5 to 5.9) | 2.4 (−8.1 to 14.2) | 16.7 (2.6–32.7) | 9.5 (−1.7 to 22.1) |
| 35-64y | 5.4 (1.2–9.8) | 7.0 (3.7–10.3) | −0.8 (−12.5 to 12.4) | 8.7 (−1.3 to 19.7) | 11.0 (−0.4 to 23.7) | 11.0 (2.4–20.4) |
| 65 + y | 0.0 (−8.1 to 8.8) | 7.7 (0.2–15.9) | 4.8 (−18.1 to 34.1) | 9.4 (−12.6 to 37.0) | 12.9 (−11.3 to 43.8) | 35.6 (10.9–65.8) |
| Medication | ||||||
| all ages | −0.7 (−2.5 to 1.2) | 2.9 (1.4–4.5) | −4.0 (−9.2 to 1.5) | 7.9 (3.2–12.9) | −4.7 (−9.6 to 0.5) | 4.9 (0.7–9.3) |
| 0-4ya | −2.3 (−10.9 to 7.2) | −2.3 (−12.6 to 9.3) | 0.5 (−22.0 to 29.5) | −5.6 (−32.5 to 32.2) | 14.6 (−13.5 to 51.8) | −25.8 (−46.1 to 2.2) |
| 5-14y | −4.4 (−11.1 to 2.9) | 3.4 (−4.5 to 11.8) | −13.0 (−29.9 to 7.9) | 32.9 (4.7–68.6) | −18.3 (−33.8 to 0.9) | 10.3 (−12.0 to 38.4) |
| 15-24y | −5.0 (−10.7 to 1.0) | 3.5 (−1.2 to 8.4) | 1.5 (−14.1 to 20.0) | 8.4 (−5.4 to 24.2) | −24.5 (−37.6 to −8.6) | 4.0 (−8.5 to 18.3) |
| 25-34y | 1.3 (−4.1 to 7.1) | 3.2 (−0.7 to 7.3) | −5.5 (−19.7 to 11.1) | 1.1 (−9.8 to 13.3) | 4.7 (−9.8 to 21.6) | 12.7 (1.6–25.0) |
| 35-64y | 0.4 (−2.4 to 3.3) | 2.3 (0.2–4.5) | −4.6 (−12.3 to 3.8) | 9.5 (2.8–16.6) | −1.1 (−8.6 to 7.0) | 1.2 (−4.6 to 7.2) |
| 65 + y | −0.5 (−4.4 to 3.6) | 4.4 (0.8–8.2) | −2.7 (−13.9 to 10.0) | 5.6 (−5.4 to 18.0) | −7.0 (−16.5 to 3.6) | 11.6 (1.6–22.6) |
| Unspecified | ||||||
| all ages | 5.9 (8.8–6.8) | 7.7 (16.16–8.6) | 2.6 (0.1–5.3) | 3.9 (1.2–6.7) | 5.6 (3.4–7.8) | 9.4 (7.1–11.8) |
| <1y | 6.2 (1.1–11.6) | 7.9 (9.9–14.0) | 0.2 (−14.3 to 17.1) | 1.0 (−15.3 to 20.4) | 1.0 (−10.9 to 14.5) | 4.0 (−9.4 to 19.4) |
| 1-4y | 6.2 (2.2–8.8) | 4.5 (10.10–8.1) | 0.4 (−7.2 to 8.6) | 0.4 (−9.2 to 11.0) | 6.9 (0.3–14.0) | 12.7 (3.0–23.3) |
| 5-14y | 6.6 (3.3–8.6) | 10.2 (11.11–12.8) | 6.5 (0.6–12.8) | 4.7 (−3.0 to 13.0) | 4.4 (−0.3 to 9.4) | 8.2 (2.3–14.4) |
| 15-24y | 6.9 (4.4–9.2) | 10.0 (12.12–12.1) | 1.3 (−5.1 to 8.2) | 7.4 (1.1–14.2) | 7.6 (1.8–13.7) | 13.6 (8.2–19.3) |
| 25-34y | 6.8 (5.5–9.1) | 5.8 (13.13–8.0) | 2.9 (−3.9 to 10.2) | 1.8 (−4.5 to 8.5) | 7.7 (1.8–13.9) | 9.2 (3.6–15.1) |
| 35-64y | 4.1 (6.6–5.6) | 7.7 (14.14–9.2) | 2.5 (−1.9 to 7.0) | 2.8 (−1.7 to 7.6) | 3.1 (−0.7 to 7.1) | 8.0 (4.2–12.0) |
| 65 + y | 8.2 (7.7–11.7) | 4.4 (15.15–7.7) | −1.0 (−10.8 to 9.9) | 8.1 (−1.8 to 18.9) | 11.3 (3.0–20.3) | 7.8 (−0.5 to 16.8) |
95% CI, 95% confidence interval.
a
Trends are shown for 2010–2019 only, as data for 2020 was incomplete and was likely impacted by COVID-19 lockdowns.