Table 2.

Summary of BIM compounds solved as ligands in kinase crystal structures [74,81,82,83,84,85,86,87,88,89,90,91,92,93,94].

BIM-Type Ligand	Kinase	Family	PDB	Reference
BIM-I	PDK1	AGC	1UU8	[74]
	PIM1	CAMK	1XWS	[81]
	PIM1	CAMK	2BIK	[82]
	PIM1	CAMK	2BIL	[83]
	PKC-1	AGC	1ZRZ	[84]
BIM-II	PDK1	AGC	1UU7	[74]
	PDK1	AGC	3ORZ	[85]
	PDK1	AGC	3OTU	[85]
BIM-III	PDK1	AGC	1UU9	[74]
BIM-VII	DMPK1	AGC	2VD5	[86]
BIM-VIII	PDK1	AGC	1UVR	[74]
Ruboxistaurin 61	PDK1	AGC	1UU3	[74]
	PIM1	CAMK	2J2I	[87]
BfIM 71	GSK-3β	CMGC	3SD0	[88]
	PKC-β	AGC	2I0E	[89]
	GSK-3β	CMGC	2OW3	[90]
Indolyl phenyl maleimide 94	GSK-3β	CMGC	1R0E	[91]
Indolyl pyrimidinyl maleimide 95	JAK3	TK	3PJC	[92]
Indolyl pyrroloquinolinyl maleimide 96	MET	TK	3RHK	[93]
Indolyl quinazolinyl maleimide 97	PKC-α	AGC	3IW4	[94]