Figure 7.

Nosustrophine improves motor coordination in AD mouse models. Rotarod results of motor coordination and balance test of EB/3xTg-AD transgenic mice during four weeks. Notice the progressive decrease in rotarod performance that is directly related to the age of the mice. Latency to fall on the rotarod apparatus was significantly improved in mice treated with Nosustrophine, mainly in later stages as groups B (* p < 0.05) and C (** p < 0.01). Significant values represent means of latency of all mice in each group/trial and are expressed as standard error of the mean (±SEM).