Table 7.

Binding free energy calculations of 7d and their controls with α-glycosidase proteins.

Types of Binding Free Energy	7d–AG Complex	Acarbose–AG Complex	7d–AM Complex	Acarbose–AM Complex
	Values (kJ/mol)	Values (kJ/mol)	Values (kJ/mol)	Values (kJ/mol)
Van der Waal energy	−228.101	−218.605	−129.410	−150.112
Electrostatic energy	−21.317	−4.761	−11.217	−10.911
Polar solvation energy	122.686	−103.307	59.185	60.951
SASA energy	−19.612	−17.835	−26.185	−15.929
Binding energy	−186.186	−137.894	−159.136	−112.119

Note: AG: α-glycosidase, AM: α-amylase.