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. 2023 Sep 20;15(3):548–559. doi: 10.3390/pediatric15030050

Table 4.

Threshold values of PCT, IL-6, I/T index, PLT and the combination PCT ≥ 0.46 + IL-6 6 ≥ 4.97+ I:T index ≥ 0.335 + PLT ≤ 161.5 to distinguish Group 1 from groups 0 and 2, and validation criteria values.

Parameter Threshold Value Sensitivity (%) Specificity (%) Positive Predictive Value (%) Negative Predictive Value (%) Accuracy (%)
PCT ≥0.46 * 76 74 64 84 75
PCT ≥0.5 71 74 63 81 73
IL-6 ≥27.5 * 78 70 56 87 73
I:T index ≥0.335 * 50 80 59 74 69
I:T index ≥0.25 20 97 80 68 69
PLT ≤161.5 43 97 90 76 78
PCT + IL-6 + I:T index + PLT ≥0.276 * 94 68 63 95 78
PCT + IL-6 ≥0.206 * 94 56 53 95 69

* These threshold values are calculated using data from the present study.