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The synthesis of amine-terminated poly(N-isopropylacrylamide) (PNIPAM-NH2) using 2-aminoethanethiol (AET) as a chain transfer agent during free radical polymerization of N-isopropylacrylamide (NIPAM) (A), and the conjugation of PNIPAM-NH2 to HA to synthesize hyaluronic acid-g-poly(N-isopropylacrylamide (HPN) (B).
