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. 2023 Sep 21;16(9):1331. doi: 10.3390/ph16091331

Table 6.

Results of the analysis of the susceptibility of compounds 2 and 6 to decomposition in oxidising conditions, along with the ICH classification stress test.

Environment Sample C0
[μg/mL]
Ct
[μg/mL]
% Decomposition ICH
Classification
2
MeOH Protected 15.0 4.8 68.2
Not Protected 15.0 0 100 Photolabile
6
MeOH Protected 15.0 13.8 7.9
Not Protected 15.0 0 100 Photolabile
Environment Sample Dose
[lux·h]
Compatibility of the IR spectrum with the spectrum before irradiation ICH
classification
2
Solid phase Protected 1.2 × 106 0.9995
Not Protected 1.2 × 106 0.9404
Protected 6.0 × 106 0.9994
Not Protected 6.0 × 106 0.9017 Photolabile
6
Solid phase Protected 1.2 × 106 0.9997
Not Protected 1.2 × 106 0.9962
Protected 6.0 × 106 0.9993
Not Protected 6.0 × 106 0.9752 Photolabile