Table 3.
Cytotoxicity tests of EECR95 on macrophages (RAW264.7), mouse fibroblasts (L-929), and human gingival fibroblasts (HGF-1).
Concentration (μg/mL) | Cell Viability (% of Control) | ||
---|---|---|---|
RAW264.7 | L-929 | HGF-1 | |
10 | 103.25 ± 5.4 a | 101.2 ± 0.6 a | 101.49 ± 7.9 a |
50 | 99.32 ± 5.4 a | 109.7 ± 5.2 a | 100.59 ± 3.2 a |
100 | 98.34 ± 8.1 a | 104.9 ± 5.6 a | 100.36 ± 3.1 a |
200 | 98.10 ± 5.8 a | 97.4 ± 6.9 a | 104.21 ± 4.6 a |
500 | 97.51 ± 7.7 a | 102.4 ± 1.0 a | 108.06 ± 4.8 a |
1000 | 95.71 ± 6.7 a | 103.1 ± 3.8 a | 90.51 ± 10.2 a |
Cells were pretreated with EECR95 (10–1000 μg/mL) and then incubated for 24 h. The viability was measured by MTT assay. The results are expressed as means ± SD; values (n = 3) in each column not sharing the same superscript letter are significantly different (p < 0.05).