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. 2023 Sep 12;28(18):6577. doi: 10.3390/molecules28186577

Table 3.

Application of novel green solvents in flavonoid extraction.

Title
Compounds
Species Composition Auxiliary
Extraction
Extraction Effect References
Daidzein, genistein, puerarin NADESs ChCl/citric acid - NADESs extract had higher antioxidant activity than methanol extract and significantly reduced the degradation of isoflavones. [83]
Puerarin NADESs L-Pro/malic acid - The extraction amount of NADESs was 2.2 times higher than that of water and also significantly higher than that of methanol. The bioavailability of the extract was 323% of the aqueous extract. [84]
Puerarin IL 1-normal-butyl-3-
methylimidazolium chloride
MAE The extraction rate of puerarin was 4.201%, which was three times higher than that of the traditional extraction method. [75,85]
Flavonoids IL 1-Butyl-3-methylimidazolium bromide UAE The extraction amount of pueraria flavonoids was 774.95 mg/g. [86]
Puerarin
isoflavones
NADESs Choline chloride to citric acid of 1:2 - The amount of isoflavones in KR was measured to be 1.09 ± 0.006% overall. [81]
Puerarin IL 1-butyl-3-methylimidazolium bromide aqueous solution UAE The proposed ILUAE offered shorter extraction time and remarkably higher efficiencies [82]

-: Not reported.