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. 2023 Aug 22;15(9):2178. doi: 10.3390/pharmaceutics15092178

Table 7.

Effect of C. citrinus on morphometric parameters, obesity markers, and biochemical determinations in rats.

Measurements Control Control + Vehicle Control + C. citrinus Extract (200 mg/kg) Hypercaloric-fat Diet (HFD) HFD + Orlistat (5 mg/kg) HFD + C. citrinus Extract (250 mg/kg) HFD + Phytosomes (50 mg/kg) HFD + Phytosomes (100 mg/kg) HFD + Phytosomes (200 mg/kg)
Morphometric parameters
Abdominal circumference (cm) 20.50 ± 0.45 a 20.50 ± 45 a 21.00 ± 0.45 a 25.50 ± 0.45 b 22.25 ± 0.45 a 20.33 ± 1.36 a 21.0 ± 0.52 a 21.20 ± 20 a 21.50 ± 0.45 a
Nose-to-anus length (cm) 25.25 ± 0.60 a 24.37 ± 0.60 a 24.60 ± 0.54 a 24.41 ± 0.91 a 23.66 ± 0.91 a 24.41 ± 0.91 a 23.80 ± 0.54 a 24.12 ± 0.60 a 23.50 ± 0.60 a
Nose-to-tail length (cm) 46.40 ± 0.42 a 46.40 ± 0.42 a 46.87 ± 0.47 a 45.66 ± 0.38 a 45.71 ± 0.47 a 44.66 ± 1.63 a 45.87 ± 0.47 a 45.75 ± 0.47 a 45.12 ± 0.47 a
Markers of obesity
BMI (kg/m2) 0.67 ± 0.03 b 0.72 ± 0.03 ab 0.70 ± 0.03 ab 0.88 ± 0.04 a 0.72 ± 0.04 ab 0.69 ± 0.09 b 0.66 ± 0.04 b 0.68 ± 0.04 b 0.76 ± 0.04 ab
Adiposity index 2.78 ± 0.55 c 2.77 ± 0.55 c 2.52 ± 0.62 c 9.43 ± 0.62 a 5.56 ± 0.71 bc 6.18 ± 0.39 b 5.98 ± 0.71 b 4.82 ± 0.71 bc 4.02 ± 0.62 bc
Lee index 0.30 ± 0.01 0.30 ± 0.02 0.30 ± 0.01 0.33 ± 0.01 a 0.30 ± 0.01 0.30 ± 0.01 0.29 ± 0.01 0.30 ± 0.01 0.31 ± 0.01
Biochemical parameters
Triacylglycerol (mg/dL) 90.66 ± 11.64 c 103.66 ± 11.64 c 109.66 ± 11.64 c 202.66 ± 11.64 a 90.66 ± 11.64 c 136.33 ± 66.96 b 103.50 ± 11.64 c 105.33 ± 11.64 c 118.66 ± 11.64 b
Blood glucose (mg/dL) 93.99 ± 8.24 a 101.37 ± 8.24 a 95.59 ± 8.24 a 111.11 ± 8.24 b 100.24 ± 8.24 a 97.00 ± 4.24 a 104.18 ± 8.24 a 92.24 ± 8.24 a 96.65 ± 8.24 a
Total cholesterol (mg/dL) 161.33 ± 2.69 a 160.33 ± 2.69 a 162.00 ± 2.69 a 159.66 ± 2.69 a 156.66 ± 2.69 a 162.00 ± 2.69 a 155.66 ± 2.69 a 161.00 ± 2.69 a 159.30 ± 2.69 a

Values expressed as mean ± SEM (n = 6, ANOVA followed by Tukey test, statistically different values (a, b, c) between groups; p ≤ 0.05).