Table 7.
Measurements | Control | Control + Vehicle | Control + C. citrinus Extract (200 mg/kg) | Hypercaloric-fat Diet (HFD) | HFD + Orlistat (5 mg/kg) | HFD + C. citrinus Extract (250 mg/kg) | HFD + Phytosomes (50 mg/kg) | HFD + Phytosomes (100 mg/kg) | HFD + Phytosomes (200 mg/kg) |
---|---|---|---|---|---|---|---|---|---|
Morphometric parameters | |||||||||
Abdominal circumference (cm) | 20.50 ± 0.45 a | 20.50 ± 45 a | 21.00 ± 0.45 a | 25.50 ± 0.45 b | 22.25 ± 0.45 a | 20.33 ± 1.36 a | 21.0 ± 0.52 a | 21.20 ± 20 a | 21.50 ± 0.45 a |
Nose-to-anus length (cm) | 25.25 ± 0.60 a | 24.37 ± 0.60 a | 24.60 ± 0.54 a | 24.41 ± 0.91 a | 23.66 ± 0.91 a | 24.41 ± 0.91 a | 23.80 ± 0.54 a | 24.12 ± 0.60 a | 23.50 ± 0.60 a |
Nose-to-tail length (cm) | 46.40 ± 0.42 a | 46.40 ± 0.42 a | 46.87 ± 0.47 a | 45.66 ± 0.38 a | 45.71 ± 0.47 a | 44.66 ± 1.63 a | 45.87 ± 0.47 a | 45.75 ± 0.47 a | 45.12 ± 0.47 a |
Markers of obesity | |||||||||
BMI (kg/m2) | 0.67 ± 0.03 b | 0.72 ± 0.03 ab | 0.70 ± 0.03 ab | 0.88 ± 0.04 a | 0.72 ± 0.04 ab | 0.69 ± 0.09 b | 0.66 ± 0.04 b | 0.68 ± 0.04 b | 0.76 ± 0.04 ab |
Adiposity index | 2.78 ± 0.55 c | 2.77 ± 0.55 c | 2.52 ± 0.62 c | 9.43 ± 0.62 a | 5.56 ± 0.71 bc | 6.18 ± 0.39 b | 5.98 ± 0.71 b | 4.82 ± 0.71 bc | 4.02 ± 0.62 bc |
Lee index | 0.30 ± 0.01 | 0.30 ± 0.02 | 0.30 ± 0.01 | 0.33 ± 0.01 a | 0.30 ± 0.01 | 0.30 ± 0.01 | 0.29 ± 0.01 | 0.30 ± 0.01 | 0.31 ± 0.01 |
Biochemical parameters | |||||||||
Triacylglycerol (mg/dL) | 90.66 ± 11.64 c | 103.66 ± 11.64 c | 109.66 ± 11.64 c | 202.66 ± 11.64 a | 90.66 ± 11.64 c | 136.33 ± 66.96 b | 103.50 ± 11.64 c | 105.33 ± 11.64 c | 118.66 ± 11.64 b |
Blood glucose (mg/dL) | 93.99 ± 8.24 a | 101.37 ± 8.24 a | 95.59 ± 8.24 a | 111.11 ± 8.24 b | 100.24 ± 8.24 a | 97.00 ± 4.24 a | 104.18 ± 8.24 a | 92.24 ± 8.24 a | 96.65 ± 8.24 a |
Total cholesterol (mg/dL) | 161.33 ± 2.69 a | 160.33 ± 2.69 a | 162.00 ± 2.69 a | 159.66 ± 2.69 a | 156.66 ± 2.69 a | 162.00 ± 2.69 a | 155.66 ± 2.69 a | 161.00 ± 2.69 a | 159.30 ± 2.69 a |
Values expressed as mean ± SEM (n = 6, ANOVA followed by Tukey test, statistically different values (a, b, c) between groups; p ≤ 0.05).