Figure 4.

CTD tetramer transparency and traceability. Every generated CGPD-tetramer includes an “Evidence” column with a hyperlinked “Supporting Lines of Evidence,” providing both transparency and traceability as to how the tetramer was generated. The first 4 supporting lines of evidence (C-G, C-P, C-D, and G-D) are direct interactions annotated by CTD biocurators from the literature, and all the supporting interaction statements as well as the PubMed article identifiers (from whence the interactions were curated) are listed. The fifth supporting line of evidence (G-P) is electronically imported from gene-GO annotations provided by NCBI.