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. 2023 Aug 29;16(9):1220. doi: 10.3390/ph16091220

Table 1.

Comparison of the results of light–dark box model (time spent and number of entries into lightbox) and open field test (number of quadrants invaded and central compartment resting time) among the different treated and control groups.

Groups Light Dark Box Model Open Field Test
Time Spent in Light Box Number of Entries in the Lightbox Number of Quadrant Invasion Central Compartment Resting Time
Positive control 144 ± 73 5 ± 2 76 ± 19 11 ± 9
Negative control 52 ± 34 2 ± 2 19 ± 5 2 ± 2
LSP dispersion 76 ± 32 4 ± 1 44 ± 12 3 ± 2
LSP-NLCs 119 ± 10 * 7 ± 2 * 75 ± 22 ** 6 ± 2 *

Data are presented as mean ± S.D (n = 3). Data were analyzed by one-way ANOVA followed by Dunnett’s test. * p < 0.05, ** p < 0.01 among treated vs. negative control.