Summary of Section 12: Control of FCoV and FIP  As FCoV is transmitted predominantly via the faecal–oral route, hygiene is the mainstay of FCoV (and therefore FIP) control. FCoV infection is maintained in households by continual cycles of infection and re-infection and is less of a problem amongst cats with access outdoors that bury their faeces outside. A reduction of FCoV infection pressure can also be helped by not keeping more than three well-adapted (consistent) cats per room and providing outdoor access. If outside access is not possible, the number of litter trays should be one more than the number of cats present. Litter trays should be positioned in different rooms, away from food and water, have faeces removed twice a day and completely cleaned once weekly. Non-tracking clumping bentonite-based Fuller’s earth cat litter can be helpful to reduce FCoV spread.  The identification and separation of FCoV shedders can be helpful for reducing transmission rates of FCoV in a household. No universally accepted protocol for identification of shedders exists, and testing results represent the situation at only that timepoint, with changes in results occurring over time. Although positive correlation exists between FCoV serum antibody titres and the likelihood and the frequency of faecal FCoV shedding, as well as the FCoV faecal viral load, this relationship is not straightforward. Serum antibody-negative cats can be positive for FCoV RNA in faeces and serum antibody-positive cats can be negative for FCoV RNA in faeces.  The use of nucleoside analogues, such as GS-441524, to eliminate FCoV shedding in cats without FIP is very controversial. Some suggest there is a potential risk of development of drug-resistant escape mutant FCoVs, and are concerned that clearing a household of FCoV is difficult to achieve and maintain, due to the high prevalence of FCoV infection in cat populations. Those wishing to eradicate FCoV from their household should be reminded of the importance of both hygiene and keeping cats in small groups, as well as other measures to reduce FCoV load (e.g., non-tracking litter, avoiding stress) and the use of quarantine and testing prior to introducing cats or kittens into households.  The commercially available genetic PCR tests that purport to detect cats that are resistant to FIP are currently not recommended as a basis for breeding decisions as they are not accurate in identifying resistant cats.  Stress experienced by FCoV-infected cats (e.g., due to surgery, boarding, adoption) or immunosuppression caused by infections, e.g., FIV or FeLV, can predispose cats to developing FIP, so the minimisation of stress and immunosuppression are important to prevent the development of FIP in FCoV-infected cats. The FIP vaccine is not useful in FCoV-infected cats.