Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The co-crystal structure of compound 12 bound to ALK L1196M protein (PDB 4CD0, 2.23 Å). Interaction of compound 12 into the binding site of the protein. The protein is depicted as yellow ribbons, and the hydrogen bonds are illustrated with blue dashed lines. Compound 12 atoms are colored as follows: carbon, red-orange; nitrogen, blue; oxygen, red; chlorine, green; fluorine, jade; hydrogen, white; the chiral carbon is highlighted in violet.
