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. 2023 Sep 17;15(18):4023. doi: 10.3390/nu15184023
Mitochondria: BCAA + 2-OG → BCKA + Glu
Glu + OA → 2-OG + L-Asp
AGC1: L-Asp transport to the cytosol
Cytosol: L-Asp + IMP + GTP → adenylosuccinate + GDP + Pi
adenylosuccinate → fumarate + AMP
AMP + H2O → IMP + NH3
or
AMP + ATP → ADP + ADP
ADP + creatine phosphate → ATP + creatine