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. 2023 Sep 15;11(9):1491. doi: 10.3390/vaccines11091491

Table 4.

Factors influencing vaccine uptake.

Table Factors Barriers Facilitators
Intrapersonal Level
Vaccine related factors Vaccine safety Safety concerns [23,25,33,48,50,51,55,56,57,60,61,65,66,67,68,69,70,72,74,75,76,77,78,81,82,83,84,85,86,88,91,92,95] Confident in the COVID-19 vaccines [47,52,88]
Vaccine efficacy Concerns about the effectiveness of the vaccine [23,25,65,67,69,70,76,77,78,82,84,85,86,88,92,95] Belief that the vaccine is effective in protecting against COVID-19 [74]
Vaccine knowledge Having poor knowledge [66]
Vaccine perception Having a negative perception [43]
Vaccine preference Prefer to wait for another type of COVID-19 vaccine [70]
Vaccine necessity Not a priority [70]
Vaccine experiences Experiences of discomfort while receiving the first dose [95]
Vaccine immunity against COVID-19 Sufficient immunity with the first dose [95]
Vaccine vs. alternative treatment Preferred alternative treatment to the COVID-19 vaccine [61,81,95]
Vaccine development Mistrust in science [23,47,55,56,61,66,68,69,70,74,75,77,81,82,85,90,91]
COVID-19 Diagnosis of COVID Prior diagnosis [23,67,91,92]
Susceptibility of contracting COVID Low perceived susceptibility [23,66,67,78,91] High perceived susceptibility [25,47,59,63,87,92]
Side-effects of COVID Previous history of loss of smell & taste [56]
Protection against COVID Belief in one’s immune system [65,68,76,77,95] Requires the vaccine to protect oneself [60,72,74,78,84,88,91]
Psychosocial factors Chronic illness Presence of chronic illness [56] Presence of chronic illness [59]
Family planning Planning pregnancy [67,70,91]
Religion Religious beliefs [55,56,61,66,70,81,95]
Experiences with vaccines Prior adverse reactions to vaccines [2,61]
Fear of needles & injections [70]
Against vaccinations in general [91]
Interpersonal Level
Influences Relationship with colleagues Being influenced by colleagues [63]
Relationship with family Requires permission from their family before taking the COVID-19 vaccine [70]
Disapproval from family [66]
Desire to protect loved ones [25,60,72,78,84,88,91,92]
Loss of someone to COVID-19 [55]
Relationship with religious leaders Discouragement from Religious leaders [66]
Organizational Level
Institutional structures Government & stakeholders Lack of trust [25,43,56,57,68,81,90]
Government officials not accepting vaccine uptake [66]
Vaccine accessibility COVID-19 vaccine inaccessible [63,65,70,75] COVID-19 vaccine accessible [63]
Workplace environment Company policy To keep working [91]
Leadership & support Lack of support by employer [66]
Community Level
Shared norms & myths Public health responsibility To end the pandemic [52,78,91,92]
Access to information Lack of information [23,25,57,61,63,67,70,78]
Social media Subscribing to misinformation or conspiracies [57,60,63,68,70,72,90]
Policy Level
Vaccination policies Travel requirements Requires the vaccine for future travel [47,60,63]
Vaccination cost Vaccines are provided free of charge [74,88]
Mandatory policies Feeling coerced into accepting vaccines [82,89]