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. 2023 Sep 19;13(9):1023. doi: 10.3390/metabo13091023

Table 7.

Gene Ontology domains enriched in differentially expressed genes in muscle samples from cows that were high feed efficient (HE; n = 8) compared with low feed efficient (n = 8) 1.

Gene Ontology Domain ID Genes Fold
Enrichment
Corrected
p-Value
Upregulated in HE
 Cell Component: extracellular space GO:0005615 19 2.9 0.0130
 Molecular Function: actin filament binding GO:0051015 8 5.3 0.0140
Downregulated in HE
 Cell Component: nucleus GO:0005634 44 1.9 0.0061

1 Enrichment analysis was performed using the Database for Annotation, Visualization, and Integrated Discovery (v. 2021) by comparing differentially expressed genes (mean read count ≥ 10; p-value ≤ 0.05; fold change ≥1.5). Fold enrichment and Benjamini corrected p-values are reported.