Figure 1.

Parasitic growth curve (as measured by percentage of infected red blood cells) in humanized FRG mice engrafted with human hepatocytes and erythrocytes, after infection with cryopreserved P. falciparum SPZ at two (A) or three (B) inoculum doses. Two separate studies (A,B) were performed using one mouse (n = 1) per inoculum. The same batch was used for both studies.