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. 2023 Sep 15;15(9):1932. doi: 10.3390/v15091932

Table 3.

Positive and Negative Correlations Involving Signature DTG-Selected DRMs 1.

DRM A DRM B A and B A Alone B Alone Neither Spearman Rho p Value
Positively correlated DRMs 2
G140S Q148H 3 1 0 95 0.86 <0.001
G140A Q148K 2 2 2 93 0.48 <0.001
G140A Q148R 2 2 3 92 0.42 <0.001
T66A G118R 5 0 23 70 0.37 <0.001
S147G N155H 4 4 9 82 0.32 0.001
E157Q R263K 7 0 40 52 0.29 0.004
S147G Q148R 2 6 3 88 0.27 0.007
G118R E138K 8 17 8 62 0.24 0.02
L74M G118R 2 0 25 70 0.23 0.02
G140S N155H 2 2 11 84 0.22 0.03
T97A N155H 2 2 11 84 0.22 0.03
A49G R263K 4 0 43 52 0.22 0.03
L74I G118R 3 1 25 69 0.21 0.04
Negatively correlated DRMs 3
G118R R263K 3 24 42 28 −0.44 <0.001
E138K R263K 2 16 43 36 −0.34 <0.001
Q148KRH R263K 0 11 46 41 −0.33 <0.001
N155H R263K 2 11 45 41 −0.25 0.01
G118R N155H 0 29 13 57 −0.25 0.01
T66I R263K 0 6 47 46 −0.24 0.02
G118R Q148KRH 0 28 11 59 −0.23 0.03

Footnote: 1 DRMs present as part of mixtures were excluded from analysis. 2 Only those pairs present in ≥2 PLWH were analyzed. 3 For this analysis Q148H/K/R were pooled.