Table 4.
Correlation between TPC, TFC, TPA, groups of polyphenolic compounds identified in the Eriobotrya japonica leaf extract and antioxidant (ABTS, CUPRAC), and antiproliferative (Caco-2, HT-29, MCF-7, U87MG) activity.
| ABTS | CUPRAC | ChA | O2˙− | OH− | Caco-2 | HT-29 | MCF-7 | U87MG | TPC | TFC | TPA | Phenolic Acid | Flavonols | Flavones | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABTS | 1.000 | 0.995 * | 0.793 | −0.704 | 0.711 | 0.782 | −0.175 | 0.817 | −0.508 | −0.957 | −0.137 | 0.056 | 0.997 * | 0.629 | 0.511 |
| CUPRAC | 1.000 | −0.640 | −0.532 | 0.540 | 0.899 | −0.386 | 0.671 | −0.308 | −0.871 | −0.350 | −0.162 | 0.995 * | 0.783 | 0.687 | |
| ChA | 1.000 | 0.991 | −0.992 | −0.240 | −0.460 | −0.999 * | 0.927 | 0.935 | −0.494 | −0.653 | 0.063 | −0.025 | 0.117 | ||
| O2•− | 1.000 | −0.999 * | −0.109 | −0.574 | −0.984 | 0.969 | 0.879 | −0.605 | −0.748 | 0.195 | 0.107 | 0.248 | |||
| OH− | 1.000 | 0.118 | 0.567 | 0.986 | −0.966 | −0.883 | 0.598 | 0.742 | −0.186 | −0.098 | −0.239 | ||||
| Caco-2 | 1.000 | −0.750 | 0.280 | 0.138 | −0.569 | −0.724 | −0.577 | 0.953 | 0.976 | 0.935 | |||||
| HT-29 | 1.000 | 0.423 | −0.758 | −0.116 | 0.999* | 0.972 | −0.914 | −0.875 | −0.995 * | ||||||
| MCF-7 | 1.000 | −0.911 | −0.948 | 0.457 | 0.621 | −0.022 | 0.066 | −0.076 | |||||||
| U87MG | 1.000 | 0.735 | −0.785 | −0.888 | 0.431 | 0.349 | 0.479 | ||||||||
| TPC | 1.000 | −0.154 | −0.342 | −0.294 | −0.378 | −0.241 | |||||||||
| TFC | 1.000 | 0.981 | −0.898 | −0.856 | −0.921 | ||||||||||
| TPA | 1.000 | −0.796 | −0.740 | −0.828 | |||||||||||
| Phenolic acids | 1.000 | 0.996 | 0.998 | ||||||||||||
| Flavonols | 1.000 | 0.989 | |||||||||||||
| Flavones | 1.000 |
(−) negative correlation, * significant differences at p < 0.05. TFC = Total Flavonoid Content; TPA = Total Proanthocyanidin Content; TPC = Total Phenol Content.