| NPs | Nanoparticles |
| IASP | International Association for the Study of Pain |
| RA | Rheumatoid arthritis |
| CBD | Cannabidiol |
| BCP | Beta-caryophyllene |
| NSAIDs | Nonsteroidal anti-inflammatory drugs |
| COX | Cyclooxygenase |
| MTX | Methotrexate |
| OA | Osteoarthritis |
| DAMGO | [D-Ala2, NMe-Phe4, Gly5-ol]-enkephalin |
| N/OFQ | Nociception/orphanin FQ |
| NOP | N/OFQ receptor |
| SLNs | Solid lipid nanoparticles |
| NLCs | Nanostructured lipid carriers |
| PAMAM | Poly(amidoamine) |
| PLGA | Poly(lactic-co-glycolic acid) |
| PEG | Polyethylene glycol |
| MSNs | Mesoporous silica nanoparticles |
| DOPr | δ-opioid receptor |
| SD | Sprague Dawley |
| CEL | Celonol |
| INdo | Indomethacin |
| IL-1ꞵ | Interleukin-1ꞵ |
| TNF-α | Tumor necrosis factor-α |
| TAT | Transactivator of transcription |
| PEITC | Phenethyl isothiocyanate |
| Δ9-THC | Δ9-tetrahydrocannabinol |
| hEGF | Human epidermal growth factor |
| PTT | Photothermal therapy |