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Analysis of selection pressures of the SARS-CoV-2 Omicron subvariants. Positive selection pressure assessed using the IFEL method. Major mutations compared to BA.2 are indicated in bold letters.
| Amino Acid Changes | |
| Val3Gly | |
| Ala83Val | |
| His146Gln | |
| Gln180Glu | |
| Glu183Val | |
| Gly213Glu | |
| Gly252Val | |
| RBD | Asp339His |
| Arg346Thr | |
| Leu368Ile | |
| Asn417Lys | |
| Lys440Asn | |
| Val445Pro, Ala | |
| Gly446Ser | |
| Leu452Arg | |
| Asn460Lys, Ser | |
| Lys478Arg | |
| Phe486Val, Pro, Ser | |
| Phe490Ser | |
| Arg493Gln | |
| Pro521Thr, Gln | |
| Asn658Ser |
