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. 2023 Aug 25;11(9):1420. doi: 10.3390/vaccines11091420

Figure 2.

Figure 2

Antigen-specific antibody titers in mice immunized with the mixture of A29L, M1R, B6R, and A35R of MPXV. A29L, M1R, B6R, and A35R in combination were formulated with or without adjuvant and used to immunize mice intramuscularly. Sera of mice were sampled at days 0, 14, 28, and 90. Antigen-specific IgG antibody titers were evaluated via ELISA assays. (A) Schematic diagram of immunization and sera collection. (B) Anti-A27L antibody titers. (C) Anti-M1R antibody titers. (D) Anti-A35R antibody titers. (E) Anti-B6R antibody titers. Data are presented as means ± SEM (n = 3). *, p < 0.05; **, p < 0.01; ***, p < 0.001; ns, no significance (p > 0.05).