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. 2023 Aug 24;13(9):971. doi: 10.3390/metabo13090971

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Longitudinal trajectories of individual metabolite concentrations from 9 superpathways for a single infant transitioning off TPN. Dexpanthenol (pro-vitamin B5) was used as a marker of TPN treatment. Dashed red line indicates when the infant was fully off TPN. These trajectories encompasses the top amino acid and lipid metabolites identified in our MWAS (a), along with energy and nucleotide pathways (b), carbohydrate and cofactor/vitamin pathways (c), and peptide and partially characterized molecule super pathways (d).

Longitudinal trajectories of individual metabolite concentrations from 9 superpathways for a single infant transitioning off TPN. Dexpanthenol (pro-vitamin B5) was used as a marker of TPN treatment. Dashed red line indicates when the infant was fully off TPN. These trajectories encompasses the top amino acid and lipid metabolites identified in our MWAS (a), along with energy and nucleotide pathways (b), carbohydrate and cofactor/vitamin pathways (c), and peptide and partially characterized molecule super pathways (d).