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Phenotypes of HIV-1AD8 Env FPPR combination mutants. The phenotypes of Envs with combined changes and selected Env mutants with individual amino acid changes in the FPPR were compared to those of the wild-type HIV-1AD8 Env. Values are colored according to the key, based on their fold increase or decrease compared to those of the wt HIV-1AD8 Env. The results shown are the means and SDs derived from two independent experiments.
