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Characterization of the pain model related to diabetic neuropathy. Effect of streptozotocin (STZ, 90 mg/kg i.p.) or vehicle (Citrate) on weight (g) (A), blood glucose levels (B), and nociceptive threshold by von Frey filaments (C), (n = 6) per group. Values are expressed as the mean ± standard error of the mean (X ± SEM) measured on days 0, 7, 15, 23, 31, and 38. Student’s t-test for unpaired data, * p < 0.05.
