. 2023 Aug 31;13(9):983. doi: 10.3390/metabo13090983

Table 1.

DMs in PWB iPSCs as compared to control iPSCs.

ESI − Mode					ESI + Mode
Metabolite	HMDB_ID	VIP	Log₂(FC)	p Value	Metabolite	HMDB_ID	VIP	Log₂(FC)	p Value
Glutamine	HMDB000641	2.914	−1.742	0.013	Indoline	HMDB253472	1.891	−0.876	0.022
15-Hydro-peroxy-EPE	HMDB062295	3.286	−1.937	0.002	Asymmetric dimethylarginine	HMDB001539	1.921	−0.916	0.015
					Phenylalanylglycine	HMDB028995	2.554	−1.419	0.005
					N-Heptanoylglycine	HMDB013010	2.446	−1.648	0.031
					15-Hydroperoxy-EPE	HMDB062295	2.675	−1.561	0.012
					1,5,8-Heptadecatriene	HMDB041082	1.868	−0.770	0.001
					Histidylleucine	HMDB028889	2.820	−1.660	<0.001
					Sphingosine	HMDB000252	1.767	−0.736	0.003
Thyronine	HMDB000667	1.733	0.635	0.013	2-Heptadecylfuran	HMDB033608	1.562	0.802	0.045
Glutathione	HMDB000125	1.867	0.710	0.009	Glutathione	HMDB000125	1.549	0.677	0.046
Islatravir	HMDB253596	1.870	0.691	0.010	Thromboxane	HMDB003208	1.774	0.969	0.037
CDP	HMDB001546	1.953	0.691	0.002	11-Eicosen-1-ol	HMDB034933	1.817	0.822	0.044
Uridine diphosphate glucose	HMDB000286	1.558	0.5164	0.018	N-(14-Methylhexadecanoyl)pyrrolidine	HMDB034373	1.803	1.030	0.043
Zeatin riboside triphosphate	HMDB304509	1.645	0.594	0.021	Pipericine	HMDB031678	1.686	0.908	0.049
					4,6-Heneicosanedione	HMDB035571	2.106	1.538	0.031
					N-Palmitoyl Leucine	HMDB241928	1.537	0.629	0.048

Note: HMDB: the Human Metabolome Database; VIP: variable projection importance score (VIP > 1.5) of the metabolite in Partial Least Squares Discriminant Analysis model; Log2(FC): the log2 of fold change of the metabolites in PWB iPSCs vs. control iPSCs. If the value is greater than 0, the content of the metabolite is increased in the PWB iPSCs. p value: a statistic result from t-test comparing PWB iPSCs with the control iPSCs.