Table 1.
Compound | Date of FDA Authorisation | Natural Source | Clinical Use |
---|---|---|---|
Cytarabine | 1969 | Sponge | Leukaemia |
Fludarabine | 2004 | Sponge | Leukaemia |
Trabectedin | 2015 | Tunicate | Ovarian cancer |
Eribulin | 2010 | Sponge | Breast cancer |
Brentuximab vedotin | 2011 | Mollusk/cyanobacterium | Lymphomas |
Lurbinectedin | 2020 | Tunicate | Ovarian cancer |
Polatuzumab vedotin | 2019 | Mollusk/cyanobacterium | Breast cancer |
Enfortumab vedotin | 2019 | Mollusk/cyanobacterium | Urothelial cancer |
Belantamab mafodotin | 2020 | Mollusk/cyanobacterium | Multiple myeloma |