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. 2023 Sep 5;28(18):6450. doi: 10.3390/molecules28186450

Table 1.

Marketed drugs by FDA.

Compound Date of FDA Authorisation Natural Source Clinical Use
Cytarabine 1969 Sponge Leukaemia
Fludarabine 2004 Sponge Leukaemia
Trabectedin 2015 Tunicate Ovarian cancer
Eribulin 2010 Sponge Breast cancer
Brentuximab vedotin 2011 Mollusk/cyanobacterium Lymphomas
Lurbinectedin 2020 Tunicate Ovarian cancer
Polatuzumab vedotin 2019 Mollusk/cyanobacterium Breast cancer
Enfortumab vedotin 2019 Mollusk/cyanobacterium Urothelial cancer
Belantamab mafodotin 2020 Mollusk/cyanobacterium Multiple myeloma