Table 3.

Cytotoxic activity of compounds 2c, 2d, 2e, 2g, and 2m in DMPM and normal cells.

Compound	IC50 (µM) a
	STO	MesoII	W138
2c	0.49 ± 0.07	25.12 ± 3.06	>100
2d	0.61 ± 0.14	16.77 ± 1.99	18.76 ± 3.21
2e	0.43 ± 0.11	4.85 ± 0.64	>100
2g	0.54 ± 0.09	13.27 ± 0.74	15.44 ± 3.87
2m	0.33 ± 0.07	4.11 ± 0.22	>100

^a Data are reported as IC₅₀ values (concentration of drug required to inhibit growth by 50%) determined by MTS assay after 72 h of continuous exposure to each compound. The data represent mean values ± SD of at least three independent experiments.