Table 10.

In vitro inhibition of cancer cell lines growth by compounds 3i–p.

Cell Line	GI50 (µM) a
	3i	3j	3k	3l	3m	3n	3o	3p
Leukaemia
CCRF-CEM	1.89	1.75	1.44	2.40	2.45	2.33	2.24	0.42
HL-60(TB)	2.07	2.19	2.02	2.17	1.51	1.90	2.09	2.11
K-562	0.37	1.48	2.05	1.85	1.72	1.78	0.98	0.35
RPMI82226	1.77	1.86	1.25	2.14	2.08	2.02	2.48	2.13
Colon Cancer
HCC-2998	1.92	1.95	1.87	2.01	1.87	1.88	1.98	2.10
HCT-116	1.61	1.22	1.71	1.73	1.77	1.77	1.66	1.56
HCT-15	1.33	1.67	1.56	1.79	1.95	1.88	1.65	1.38
HT29	1.35	1.69	2.07	2.01	2.23	1.53	1.71	1.57
KM12	1.67	1.83	2.02	1.65	1.76	1.87	1.91	2.33
SW-620	1.88	2.12	1.73	1.98	1.93	1.95	2.04	1.81
Breast Cancer
MCF-7	1.48	1.27	1.43	1.22	1.66	1.81	1.53	1.77
MDA-MB-231/ATCC	1.27	1.46	1.06	1.67	1.65	1.87	1.52	2.34
HS 578T	1.71	2.26	2.00	2.21	2.15	14.7	2.23	2.47
BT-549	1.65	1.63	8.82	1.78	8.96	1.79	1.86	26.3
MDA-MB-468	1.51	1.45	0.23	ND b	1.78	1.97	1.77	1.68

^a Concentration (µM) that inhibits 50% net cell growth. ^b ND = Not Determined.