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. 2023 Sep 5;28(18):6450. doi: 10.3390/molecules28186450

Table 26.

Percentage of PMA-induced oedema inhibition in mouse ears by bis-indolyl compounds.

Compound Dose % Oedema Inhibition
Topsentin 50 µg/ear 70.6
Bromotopsentin 50 µg/ear 75.4
Topsentin monoacetate 50 µg/ear 45.8
Topsentin diacetate 50 µg/ear 42.6
Dragmacidin 50 µg/ear 64.0
Nortopsentin A 50 µg/ear 98.1
Nortopsentin B 50 µg/ear 38.2
Nortopsentin C 50 µg/ear 70.1
Hamacanthin A 50 µM 50.0
Hamacanthin B 50 µM 34.0