Table 4.

PPV, NPV, sensitivity, specificity and diagnostic accuracy for SSR-PET/CT. PPV, positive predictive value; NPV, negative predictive value.

	Biopsy	Re-biopsy (reference standard)
PPV	91.0% (95%CI: 84.8%, 95.3%)	95.5% (95%CI: 90.4%, 98.3%)
NPV	0% (95%CI: 0%, 45.9%)	0% (95%CI: 0%, 45.9%)
Sensitivity	95.2% (95%CI: 90.0%, 98.3%)	95.5% (95%CI: 90.4%, 98.3%)
Specificity	0% (95%CI: 0%, 26.5%)	0% (95%CI: 0%, 45.9%)
Accuracy	87.1% (95%CI: 80.0%, 92.1%)	91.4% (95%CI: 85.4%, 95.5%)

PPV, positive predictive value; NPV, negative predictive value

NPV and Specificity are both recorded as 0% due to the deliberate study design focusing on a patient cohort with a notably high prevalence of liver metastases.