Skip to main content
. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Neurobiol Aging. 2023 Jul 17;131:182–195. doi: 10.1016/j.neurobiolaging.2023.07.007

Figure 1. Transcriptional analysis of day 70 neurons.

Figure 1.

A. Volcano plot of the 381 upregulated and 597 down regulated genes that were significant between the neurons with and without the TTC3 alteration. Genes marked in red have a FDR < 0.05 and FC +/−1.25. B. Heat map of the 978 significantly differentially expressed genes with a false discovery rate (FDR) < 0.05 and fold change (FC) +/−1.25 C. KEGG pathway analysis showing cellular functions overrepresented in the DEGs from the parental compared to TTC3 p.S1038C derived neurons.